Histone modifications, linker Histone H1, chromatin architecture
in Freiburg
Hinweis:
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Es wird die englische Version angezeigt.
One of the major goals of post-genomic biology is to understand the molecular basis and physiological role of covalent protein modifications. We are using histones and the "histone code" as models to study protein modifications. Our aim is to identify new modifications, to decipher how these modifications are epigenetically inherited and how they can regulate gene expression and chromatin structure.
Die Beschreibung für diese Gruppe steht nur in englischer Sprache zur Verfügung.
Es wird die englische Version angezeigt.
Publikationen
Schneider, R. and Grosschedl, R. (2007) Dynamics of nuclear architecture in genome organisation and gene expression. Genes Dev., 21, 3027-3043.
Izzo, A., Kamienariaz, K. and Schneider, R. (2008) The histone H1 family: specific members, specific functions. Biol. Chem., 389, 333-343.
Hajkova, P., Waldmann, T. *, Ancelin, K. *, Lange, U.C., Lacoste, N., Cesari, F., Lee, C., Almouzni, G., Schneider, R. and Surani, A. (2008) Histone replacement underlies the process of epigenetic reprogramming in the mouse germ line. Nature, 452, 877-881.
Izzo, A., Kamienariaz, K. and Schneider, R. (2008) The histone H1 family: specific members, specific functions. Biol. Chem., 389, 333-343.
Hajkova, P., Waldmann, T. *, Ancelin, K. *, Lange, U.C., Lacoste, N., Cesari, F., Lee, C., Almouzni, G., Schneider, R. and Surani, A. (2008) Histone replacement underlies the process of epigenetic reprogramming in the mouse germ line. Nature, 452, 877-881.
Kontakt
Dr. Robert
Schneider
Max-Planck-Institute of Immunobiology
Stübeweg 51
D-79108 Freiburg, Germany
Telefon: +49 761 5108 378
Fax: +49 761 5108 221
Email:
Max-Planck-Institute of Immunobiology
Stübeweg 51
D-79108 Freiburg, Germany
Telefon: +49 761 5108 378
Fax: +49 761 5108 221
Email: