The German Research Foundation (DFG) promoted 16 particular projects dealing
with epigenetics within the scope of the Priority Program 1129 in three
funding periods from 2002 to 2008. The following projects and groups
have been involved:
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Dr. Asifa
Akhtar , Freiburg
Identification and characterization of the MOF histone acetyl transferase gene as a novel chromatin entry site on the Drosophila male X chromosome.
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Karin
Buiting, PhD , Essen
Bernhard
Horsthemke, PhD , Essen
Gene- and Imprintdefects in patients withmit Prader-Willi and Angelman syndrome
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M. Cristina
Cardoso, PhD , Darmstadt
Replication and Translation of epigenetic Information.
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Prof. Dr. Reinhard
Dammann , Gießen
Mechanisms of RASSF1A tumor suppressor gene inactivation by de novo methylation of the promoter CpG island during carcinogenesis
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Prof. Dr. Ann Elizabeth
Ehrenhofer-Murray , Essen
Reestablishment of epigenetic patterns of histone modification after DNA replication and chromatin assembly in S. cerevisiae
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Univ.-Prof. Dr. Thomas
Haaf , Würzburg
Epigenetische Reprogrammierung im frühen Embryo: Evolution, Mechanismen und Bedeutung für die Säugerentwicklung.
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Prof. Dr. Albert
Jeltsch , Bremen
DNA methylation, knock out studies, site directed mutagenesis, transgenic mice, enzymology.
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Prof. Dr. Heinrich
Leonhardt , München
Erhaltung und Modifikation der epigenetischen Information: Koordination von DNA-Replikation und Methylierung im Zellzyklus und in der Entwicklung.
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Dr. Frank
Lyko , Heidelberg
Funktionelle Charakterisierung der DNA-Methylierung in Drosophila.
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Dr. Jürg
Müller , München
Ein genetischer Screen zur Identifizierung neuer Polycomb Gruppen Gene in Drosophila melanogaster.
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Wolfgang
Nellen , Kassel
Gene silencing by RNAi and DNA Methylation.
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Dr. Martina
Paulsen , Saarbrücken
Identification of regulatory elements responsible for genomic imprinting in mammals
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Dr. Dirk
Prawitt , Mainz
Prof. Dr. Bernhard
Zabel , Mainz
Beckwith-Wiedemann syndrome and associated tumors - Identification of factors essential for imprinting mechanisms.
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Prof. Gunter
Reuter , Halle
Initiation und Stabilität des heterochromatischem Gensilencing bei Drosophila.
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Prof. Dr. Harald
Saumweber, AG-Leiter , Berlin
Formation and maintenance of euchromatic domains of interphase chromosomes.
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Prof. Dr. Jörn
Walter , Saarbrücken
DNA-methylation reprogramming during early embryogenesis and primordial germ cell development.
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Prof. Dr. Ingrid
Grummt , Heidelberg
Mechanisms that establish and propagate the epigenetic state of rRNA genes.
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